Omnitrope Somatropin (rhGH) 150 IU

Description

Omnitrope Somatropin Overview

Somatropin is a biologically identical, recombinantly synthesized version of naturally occurring human growth hormone (HGH). Produced via advanced recombinant DNA technology, it matches the exact 191-amino acid sequence found in the human body. The 150 IU bulk format is designed for intensive, longitudinal research protocols requiring consistent, high-volume dosing to observe distinct physiological shifts. In scientific literature, rHGH is the gold standard for studying the endocrine control of growth and metabolism. Research heavily focuses on its downstream effects—specifically its ability to signal the liver to secrete Insulin-like Growth Factor-1 (IGF-1), which drives cellular regeneration, increases bone mineral density, and alters how the body metabolizes lipids and carbohydrates.

Technical Specifications

• Peptide Name: Somatropin
• Synonyms: Recombinant Human Growth Hormone, rHGH, Somatotropin
• CAS Number: 12629-01-5
• Molecular Formula: C990H1528N262O300S7
• Molar Mass: ~22,125 g/mol
• Purity: ≥99.0% (determined by HPLC)
• Appearance: White to off-white lyophilized powder
• Solubility: Soluble in bacteriostatic water or sterile saline

Mechanism of Action (Research Context)
Research into Somatropin revolves around its systemic metabolic regulation:

• Direct GHR Agonism: Binds directly to growth hormone receptors present on cell membranes in muscle, fat, and liver tissues.
• Lipolysis Stimulation: Actively promotes the breakdown of triglycerides in adipocytes, significantly increasing circulating free fatty acids for energy use.
• IGF-1 Mediation: Stimulates the liver and peripheral tissues to synthesize and secrete IGF-1, mediating the compound’s potent anabolic and regenerative properties.

Storage and Handling

• Lyophilized (Powder): Store at 2°C to 8°C (36°F to 46°F). Can be stored at -20°C for longer durations. Avoid freezing if provided in liquid cartridge format.
• Reconstituted (Liquid): Once dissolved, the solution must be kept continuously refrigerated at 4°C (39°F) and utilized within 21-28 days.
• Handling: Standard laboratory safety protocols apply. This product is for laboratory research use only.

Testing and Quality Control
Every batch of Somatropin 150 IU undergoes:

1. HPLC: To ensure purity profiles strictly exceed 99.0% with minimal dimerization.
2. MS (Mass Spectrometry): To verify the exact 191-amino acid sequence.
3. Stability Analysis: To guarantee biological potency and structural integrity for critical experimental data.