BPC-157 + TB-500

Description

BPC-157 + TB-500 Blend Overview

The combination of BPC-157 (Body Protective Compound 157) and TB-500 (Thymosin Beta-4 fragment) represents the pinnacle of regenerative peptide research. While each peptide is potent individually, their combined administration is studied for a multi-pathway approach to tissue healing that neither can achieve alone.

BPC-157 is a pentadecapeptide derived from human gastric juice, noted for its stable structure and localized healing effects. TB-500 is a synthetic version of the naturally occurring 43-amino acid peptide Thymosin Beta-4, which promotes systemic cell migration and wound healing. Together, they form a “Regenerative Powerhouse” for laboratory investigation into complex injury recovery.

Technical Specifications (Per Peptide)

• BPC-157
  • Peptide Name: BPC-157 (Pentadecapeptide)
  • CAS Number: 137525-51-0
  • Molecular Formula: C62H98N16O22
  • Molar Mass: 1419.5 g/mol
• TB-500
  • Peptide Name: TB-500 (Thymosin Beta-4 Fragment)
  • CAS Number: 77591-33-4
  • Molecular Formula: C212H350N56O78S1
  • Molar Mass: 4963.5 g/mol

Purity: ≥99.0% (determined by HPLC)
Appearance: White lyophilized powder
Solubility: Soluble in sterile water or bacteriostatic water

Mechanism of Action & Synergy (Research Context)
Research focuses on the dual-action pathway of this blend:

• Angiogenesis & Vascular Expression (BPC-157): Studies investigate BPC-157’s ability to upregulate Growth Hormone receptors and promote the formation of new blood vessels (angiogenesis). This is critical for bringing nutrients to poorly vascularized tissues like tendons and ligaments.
• Actin-Binding & Cell Migration (TB-500): Research suggests TB-500 works by sequestering G-actin, which promotes cell migration to the site of injury. This allows for a systemic response, enabling the body to “recruit” the necessary components for cellular repair.
• Collagen Synthesis: The blend is often researched for its impact on Type I collagen expression, which is the primary structural protein in skin, bone, and connective tissues.
• Synergistic Healing: While BPC-157 focuses on the structural “blueprint” of the repair site, TB-500 focuses on the “labor” (migrating cells) required to complete the repair.

Storage and Handling

• Lyophilized (Powder): Store at -20°C (-4°F) for long-term stability (up to 36 months). Keep vials away from direct UV light and moisture.
• Reconstituted (Liquid): Once reconstituted, the blend should be stored at 4°C (39°F) and utilized within 14 days. Avoid vigorous shaking of the vial, as this can denature the peptide structure; instead, use a gentle swirling motion.
• Handling: Standard laboratory safety protocols apply. This product is for laboratory research use only.

Testing and Quality Control
At Flux Peptides, we guarantee the chemical integrity of our blends. Each batch of BPC-157 + TB-500 undergoes:

1. Dual HPLC (High-Performance Liquid Chromatography): To confirm the purity and correct ratio of both peptide components.
2. MS (Mass Spectrometry): To verify the molecular identity of both sequences.
3. Stability Testing: To ensure the blend maintains potency throughout the shipping process.