Flux Peptides
$0.00 0

Cart

No products in the cart.

DSIP research peptide vial
Three DSIP research peptide vials

DSIP

$40.00

DSIP (delta sleep-inducing peptide, INN emideltide) is a nonapeptide first isolated in the 1970s from the cerebral venous blood of sleeping rabbits. It is studied in animal models of sleep electroencephalography, circadian timing and the hypothalamic-pituitary-adrenal (HPA) axis.

  • Fast Domestic Shipping: Dispatched from within Canada (no customs delays)
  • Purity: ≥99.0% (HPLC tested)
  • Format: Lyophilized powder for laboratory research
  • Key Research Focus: Sleep EEG measurement, circadian timing and HPA axis studies
  • Storage: Store at minus 20 degrees Celsius, sealed and protected from light and moisture
SKU: FLX-DSIP-5MG Category:

Description

DSIP (Delta Sleep-Inducing Peptide)

DSIP is a nonapeptide, a chain of nine amino acids, described in the scientific literature since the 1970s. Its International Nonproprietary Name is emideltide. The compound takes its name from the experiments in which it was isolated: infusion into rabbits was reported to increase delta-wave activity on the electroencephalogram. It is not an approved medicine in Canada or the United States, and the material supplied here is a research chemical.

Work on DSIP spans sleep electrophysiology, neuroendocrinology and stress physiology, and is mostly in rodents and rabbits. Findings across that literature are inconsistent, and the peptide has no established receptor. It is used as a research tool rather than as a compound with a settled mechanism.

Technical Specifications

  • Peptide Name: DSIP (delta sleep-inducing peptide)
  • INN: Emideltide
  • Amino Acid Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE)
  • CAS Number: 62568-57-4
  • Molecular Formula: C35H48N10O15
  • Molar Mass: 848.8 g/mol
  • Purity: ≥99.0% (determined by HPLC)
  • Appearance: White lyophilized powder
  • Solubility: Soluble in sterile water

Research Context
Areas that have been examined in the published literature include:

  • Sleep electroencephalography: The original rabbit experiments measured delta-wave activity on the EEG, and later animal work has repeated that measurement with mixed results.
  • HPA axis: Studies have measured corticotropin-releasing hormone and corticosterone or cortisol concentrations in animals given DSIP under stress protocols.
  • Oxidative stress markers: Animal and cell studies have measured markers of lipid peroxidation and antioxidant enzyme activity after exposure to DSIP.
  • Pituitary hormone concentrations: Early neuroendocrine studies measured changes in pituitary hormone concentrations, including growth hormone, alongside DSIP administration in animals.

These are observations in laboratory models and should not be read as describing effects in a person or an animal outside a controlled study.

Storage and Handling

  • Lyophilized (powder): Store at minus 20 degrees Celsius, sealed and protected from light and moisture; see the batch documentation for the retest date.
  • Reconstituted (liquid): Keep refrigerated at 4 degrees Celsius and protected from light. The retest date in the batch documentation applies to the sealed lyophilized vial only.
  • Handling: Powder can settle on the stopper in transit, so brief centrifugation before opening helps recover the full contents. Standard laboratory safety protocols apply. This product is for laboratory research use only.

Testing and Quality Control
Every batch of DSIP is released against the following checks:

1. HPLC (high-performance liquid chromatography): to confirm a purity profile of ≥99.0%.
2. MS (mass spectrometry): to confirm the molecular weight and identity of the peptide.
3. Visual inspection: to confirm the consistency and integrity of the lyophilized cake.

For laboratory research use only. Not for human or veterinary use.

Further reading